Microneedling San Francisco
Smoother, Firmer, More Radiant Skin

MICRONEEDLING FOR COLLAGEN RENEWAL & SKIN REJUVENATION

Smoother texture, firmer skin and a naturally refreshed appearance

Microneedling, also known as collagen induction therapy, is a minimally invasive skin rejuvenation treatment that activates your skin’s natural healing response. Tiny, controlled microchannels are created in the skin, stimulating the production of new collagen and elastin—two of the building blocks that help keep skin looking smooth, firm and youthful.

As your skin naturally renews itself, microneedling can help soften fine lines, improve acne scars, minimize the appearance of enlarged pores, improve uneven skin texture and reduce the appearance of certain types of hyperpigmentation.

The result? Smoother, firmer, healthier-looking skin that continues to improve as new collagen develops.

WHAT DOES MICRONEEDLING DO AND HOW DOES IT WORK?

Microneedling uses a specialized device to create thousands of tiny, controlled microchannels in the skin. These microchannels trigger your body’s natural healing response, stimulating the production of new collagen and elastin to help renew and strengthen the skin from within.

As new collagen develops, microneedling can help smooth fine lines, soften acne scars, minimize enlarged pores, improve uneven skin texture and create firmer, more youthful-looking skin. Because the treatment works by encouraging your skin’s own natural renewal process, results continue to develop in the weeks following treatment.

Microneedling can also enhance the absorption of specially selected regenerative serums and growth factors applied during treatment, allowing us to further customize your skin rejuvenation experience.

REGENERATIVE MICRONEEDLING WITH PRF & PDGF

Take your microneedling treatment to the next level

Microneedling is already designed to activate your skin’s natural renewal process. Adding PRF or PDGF gives us another way to enhance your treatment with regenerative growth factors that support healthier, smoother and more radiant-looking skin.

PRF MICRONEEDLING — USING YOUR OWN GROWTH FACTORS

PRF (Platelet-Rich Fibrin) is created from a small sample of your own blood and contains concentrated platelets and naturally occurring growth factors. When paired with microneedling, PRF is applied to the freshly created microchannels, allowing these regenerative components to work alongside your skin’s natural healing response.

PRF Microneedling is a great choice for patients looking to improve skin texture, soften the appearance of fine lines and acne scars, and support natural collagen renewal—using growth factors derived from their own blood.

PDGF MICRONEEDLING — ADVANCED GROWTH FACTOR SKIN REJUVENATION

PDGF (Platelet-Derived Growth Factor) is a regenerative signaling protein involved in the body’s natural repair processes. When combined with microneedling, a professionally formulated PDGF product is applied to the treated skin to complement the collagen-stimulating benefits of microneedling.

PDGF Microneedling can be an excellent option for patients seeking smoother texture, improved tone, softer-looking fine lines and overall skin rejuvenation without requiring a blood draw.

WHICH IS RIGHT FOR YOU — PRF OR PDGF?

Both can be excellent additions to microneedling. PRF uses growth factors obtained from your own blood, while PDGF provides a professionally formulated growth-factor treatment without a blood draw.

During your complimentary consultation at Epi Center MedSpa in San Francisco, we can evaluate your skin, discuss your goals and recommend traditional microneedling, PRF Microneedling or PDGF Microneedling for your personalized treatment plan.

AQUAGOLD® MICRONEEDLING WITH CUSTOM SKIN INFUSIONS

AquaGold® takes microneedling to another level by combining ultra-fine, 24K gold-plated microchannels with a customized blend of skin-enhancing ingredients selected specifically for your skin. Depending on your goals, your personalized infusion may include hydrating serums, vitamins and other rejuvenating ingredients, as well as microdoses of BOTOX® when appropriate.

Unlike traditional microneedling, which primarily stimulates your skin’s natural collagen-building response, AquaGold® simultaneously creates tiny microchannels while delivering your customized skin infusion just beneath the surface.

AquaGold® can help refine enlarged pores, soften fine lines, improve skin texture, boost hydration and create a smoother, more radiant, glass-like complexion. With minimal downtime and a comfortable treatment experience, it’s a favorite for patients who want their skin looking fresh, luminous and event-ready.

Micro-needling with a twist: The 24K gold-plated needles are exceptionally fine, enabling precise, comfortable product delivery just beneath the surface.

Customized cocktail: You choose the formula that best fits your goals, then we deliver it via the AquaGold® system to the superficial dermis.

Note: The AquaGold® device delivers ingredients to the superficial dermis, offering a gentler, surface-level delivery compared with traditional fillers or neuromodulators. Results vary by individual.

Schedule your consultation or appointment today to discuss which AquaGold® option is right for you.

Epi Center MedSpa San Francisco|MicroNeedling

AquaGold® Microneedling Pricing

AquaGold

BASIC

^$500_Investment

Exomes
SkinCeuticals B5 Gel

Improves texture and radiance

AquaGold

SILVER

^$650_Investment

Exomes
SkinVive for ultimate hydration

Improves texture, boosts hydration, and enhances radiance

AquaGold

GOLD

^$760_Investment

Exomes
SkinVive for hydration
PLUS BOTOX® Cosmetic

Improves texture, minimizes pores, boosts hydration, and enhances radiance

AquaGold

PLATINUM

^$950_Investment

SkinVive for hydration
PLUS BOTOX® Cosmetic
PLUS PRF (Platelet-Rich Plasma) using your own stem cells

Improves texture, minimizes pores, maximizes hydration, and enhances radiance.

Schedule Your Appointment

WHY SHOULD I TRUST EPI CENTER MEDSPA?

Founded in 1998, Epi Center MedSpa is the first medical spa in the nation and has been at the forefront of advanced aesthetic medicine and skin rejuvenation for more than 28 years. Located in San Francisco’s Union Square, we were voted Best MedSpa in the Bay Area for 2026 and eight other years.

Microneedling may look simple, but beautiful results depend on choosing the right treatment depth, technique and products for your individual skin. Our experienced medical providers customize each treatment based on your skin type, concerns and goals—whether you want to improve fine lines, acne scars, enlarged pores, uneven texture, pigmentation or overall skin quality.

We also offer advanced regenerative microneedling options including PRF and PDGF, as well as customized serums, allowing us to personalize your treatment and take your skin rejuvenation to the next level.

Not sure which type of microneedling is right for you? Come see us for a complimentary consultation at Epi Center MedSpa in San Francisco. We’ll evaluate your skin, listen to what you’d like to improve and create a treatment plan designed especially for you.

Symptoms MicroNeedling Can Treat:

Fine lines and aging skin
Skin pigmentation issues
Scarring
Stretch marks
Acne scars
Cellulite
Large pores

BENEFITS OF MICRONEEDLING

Microneedling is a versatile, minimally invasive treatment that works with your skin’s natural renewal process to create smoother, firmer and healthier-looking skin.

Stimulates natural collagen and elastin production
Softens the appearance of fine lines and wrinkles
Improves acne scars and uneven skin texture
Helps minimize the appearance of enlarged pores
Improves overall skin tone and texture
Minimal social downtime
Typically a 30–60 minute treatment
Appropriate for a wide range of skin tones and types
Early improvements may be noticeable within days, with continued improvement as new collagen develops
Can be enhanced with PRF, PDGF or customized regenerative serums
Can treat the face, neck and other areas of the body

IS MICRONEEDLING RIGHT FOR ME?

If you’d like smoother, firmer and more refreshed-looking skin without surgery or extensive downtime, microneedling may be a great choice for you.

Microneedling is especially popular for improving fine lines, acne scars, enlarged pores, uneven skin texture, certain types of pigmentation and early signs of aging. By stimulating your skin’s natural production of collagen and elastin, it works from within to gradually improve the look and feel of your skin.

Because every patient’s skin is different, we’ll customize your treatment based on your skin type, concerns and goals. You can also enhance your microneedling treatment with PRF, PDGF or customized regenerative serums for an even more personalized approach to skin rejuvenation.

Not sure where to start? Schedule a complimentary microneedling consultation at Epi Center MedSpa in San Francisco, and we’ll help you choose the treatment that’s right for your skin.

Schedule Your Appointment