Kybella® FDA-Approved Double Chin Fat Reduction
Kybella® is the only FDA-approved injectable treatment designed to reduce submental fat—the stubborn fat beneath the chin commonly known as a “double chin.” Kybella destroys treated fat cells, helping create a slimmer, more defined chin and jawline.

WHAT DOES KYBELLA® DO FOR A DOUBLE CHIN?
Kybella® is an FDA-approved injectable treatment that reduces moderate to severe fat beneath the chin, commonly known as a “double chin.” At Epi Center MedSpa in San Francisco, Kybella injections are used to reduce unwanted submental fat and create a slimmer, more defined chin and jawline.
Kybella’s active ingredient is synthetic deoxycholic acid, which mimics a naturally occurring molecule in the body that helps break down and absorb dietary fat. When injected beneath the chin, Kybella® destroys targeted fat cells. Once destroyed, these cells can no longer store or accumulate fat.
Most patients need a series of Kybella treatments to achieve their desired results. Once your aesthetic goal is reached, additional treatments are generally not expected to be necessary.
WHY TRUST EPI CENTER MEDSPA FOR KYBELLA® IN SAN FRANCISCO?
Founded in 1998, Epi Center MedSpa is a pioneer in medical aesthetics and the first medical spa in the nation. Located in San Francisco’s Union Square, we have been helping Bay Area patients achieve natural-looking aesthetic results for more than 28 years.
Voted Best MedSpa in the Bay Area for 2026 and eight other years, Epi Center MedSpa combines advanced aesthetic medicine with experienced medical providers and highly personalized treatment plans.
Our Physician Assistant Natalie Eng, PA-C, participated in clinical research involving Kybella®, giving our team firsthand experience with this innovative injectable treatment. Natalie brings more than 12 years of experience in aesthetics and clinical research involving cosmetic injectables and medical devices.
For patients concerned about a double chin, our providers offer Kybella®, the FDA-approved injectable treatment for moderate to severe submental fat. During your complimentary consultation, we will evaluate your anatomy and goals and determine whether Kybella® or another treatment is the best option for you.
Symptoms Kybella Can Treat:
Double chin
Chin fat
Neck fat
Bra fat
Benefits of Kybella:
FDA-approved
Long-lasting results
30-minute visit

Is Kybella Right for Me?
Do you have a stubborn double chin that just won’t go away, no matter what you do? You’re not alone. Fat beneath the chin—also called submental fat—can be hereditary or simply part of aging or weight changes. And sometimes, diet and exercise just don’t make a difference.
That’s where Kybella® can help. Kybella is an FDA-approved injectable treatment that targets and destroys unwanted fat cells beneath the chin—without surgery. The result can be a slimmer-looking profile and a more defined chin and jawline.
If you’re considering Kybella in San Francisco, come see us for a complimentary consultation at Epi Center MedSpa in Union Square. We’ll take a look at your chin and jawline, talk about the results you’d like to achieve, and help you decide if Kybella—or another double chin treatment—is the best choice for you.
FAQs About Kybella
How much does it cost?
Your investment is typically between $750 – $1500 per treatment depending on the number of vials you need. Most patients may need additional treatment.
How many sessions are required?
Epi Center MedSpa customizes your treatment to include as many treatments as needed based on your desired chin profile. Spaced a month or more apart, patients often choose two to four sessions, depending on how much fat is actually there, to attain their desired profile.
How long does the process take?
This minimally invasive treatment typically takes 30 minutes.
How quickly do I see the results?
Most patients begin to experience visible contouring of their profile in about a month with continued improvement over 2-3 months. Multiple treatments are often required for optimal results.
How long do the results last?
Results are long-lasting once you’ve achieved your desired results because the fat cells are destroyed and don’t return. However, if you experience significant weight gain in the future, your neck area may again increase in size. Kybella is FDA approved for permanent fat reduction.
What is the downtime?
Depending on how much is used during treatment, you may experience anywhere from 1-3 weeks of swelling. Most noticeable swelling resolves after 3 to 7 days. Bruising may last up to 2 weeks.
Is it safe?
Yes. The FDA approved Kybella® in 2015.
What are the side effects?
The most common side effects of Kybella® are temporary and include swelling, bruising, pain, numbness, redness, and areas of firm tissue in the treatment area. Your provider will discuss with you all possible side effects prior to any treatment.
Who performs the treatment?
Treatments are performed by our registered nurses, nurse practitioners, and PAs.
How quickly can I get an appointment?
Often we can provide treatment within a few days to a week.
What other treatments are recommended in support of Kybella®?
We often recommend CoolSculpting® before Kybella®. We utilize the CoolSculpting® procedure for debulking the area and then use Kybella® to contour and sculpt. If you suffer from fat and loose skin under your chin and jawline, PDO Threads, Ultherapy and Morpheus are excellent options to lift and tighten the skin.



